The groundbreaking discovery of microRNA in the early 1990s by Gary Ruvkun and Victor Ambros has revolutionized the field of gene regulation, culminating in their well-deserved recognition as recipients of the 2024 Nobel Prize in Physiology or Medicine.Initially met with skepticism from the broader scientific community, microRNAs have now emerged as crucial players in the intricate ballet of RNA research, fundamentally altering our understanding of how genes translate into proteins.